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 found in a retrospective study that independent risk factorsfor developing a DFO due to Gram-negative bacteria (alone or combined with a Gram-positive isolate) were glycated hemoglobin less than 7% (odds ratio [OR]=2.0; 95%confidence interval [CI]=1.1–3.5) and a wound caused by traumatic injury (OR=2.0;95% CI=1.0–3.9). All hematopoietic or blood celllineage develop within the bone marrow microenvironmentand each cell type is groomed toward maturation within theniches of the bone marrow by exposure to specific growthfactors and cytokines, as well as cell-to-cell and cell-to-stroma interactions. Twelvepatients with DCI were studied by trending the daily mean alpha power against the modu-lation of treatment and clinical evolution
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